NEPHELOstar Plus

Microplate nephelometer for light-scattering and turbidity measurements

BMG LABTECH microplate reader NEPHELOstar Plus from the front view

The world's first and only laser-based microplate nephelometer was developed to meet high-throughput demands for fast compound solubility screens. The NEPHELOstar ® Plus detects insoluble particles in liquid samples by measuring forward scattered light and can be used for turbidity measurements, drug solubility screening , protein binding kinetics, microbial growth, and petroleum process control.

    NEPHELOstar Plus

    The NEPHELOstar Plus is a microplate nephelometer with a high-intensity laser diode. It can be up to thirty times more sensitive than traditional transmission optical density readers that measure the reduction in direct light passing through a sample well. Thanks to its speed, flexibility and performance, the NEPHELOstar Plus allows more applications to be adapted to microplate-based laser nephelometry than ever before.

    Michael Herrwerth

    People behind our Plate Readers

    In conjunction with our 30th company anniversary, we invite you all backstage and introduce the people behind our microplate readers.

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    Features

    • Adjustable laser intensity and beam diameter
    • Measurement in up to 384-well microplate format
    • Incubation up to 45 ° C or 60 ° C
    • Linear, orbital and double-orbital shaking
    • High-precision injectors with simultaneous reagent injection and detection
    • Microplate Stacker and robot compatible

    Customer success story

    Microplate reader technologies

    More about our technologies

    Automation

    Automation is a key feature in high-throughput screening. Several BMG LABTECH microplate readers have been successfully integrated into various robotic systems. Since all instruments have the same xy dimensions and plate out / in position, once automation has been designed for one BMG LABTECH reader , the solution will work for all. All plate readers can be controlled through ActiveX or DDE interfaces. Moreover, the ASCII data output is the most versatile in the industry and works with most LIMS and automation platforms.

    Backside of a microplate reader showing the gas vent

    Gas Vent

    BMG LABTECH offers two forms of gas control on its microplate readers. The Atmospheric Control Unit (ACU) for the CLARIOstar is a unique microprocessor-controlled unit that independently regulates both CO 2 and O 2 inside the microplate reader. Alternatively, the Gas Vent is a positive pressure gas purge through which the internal atmosphere of the microplate reader can be replaced.

    Schematic description of incubation and shaking

    Incubation and shaking

    Shaking and incubation allow users to mix the well content and easily run measurements at elevated temperatures. The incubator controls the air temperature in the measurement chamber from room temperature up to 45 ° C or 65 ° C. BMG LABTECH microplate readers are equipped with orbital, double-orbital or linear shaking with definable intensity, duration and direction of motion. These features are available on all BMG LABTECH plate readers.

    Open PHERAstar showing pumps for reagent injection

    Reagent injectors

    Many of today's most popular assays such as enzyme kinetics, calcium flux, and dual luciferase require the ability to monitor a signal during and after the addition of a reagent.
    All BMG LABTECH readers, with the exception of the SPECTROstar Nano , can be equipped with up to two built-in reagent injectors. Injectors enable reagent delivery to any plate format from 6 to 384 wells.

    NEPHELOstar Plus

    • Optional Accessories

    For more performance: Accessories for NEPHELOstar Plus

    • Microplate stacker directed to the left with CLARIOstar in the background

      Microplate Stacker

      Microplate handling system
    • Microplate reader accessories microplate shaker and incubator THERMOstar opened and from the front view

      THERMOstar

      Intelligent microplate incubation
    • Microplate reader accessories Atmospheric Control Unit (ACU) from the front view

      Atmospheric Control Unit

      Enhanced cell-based assays

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